It is not going to work
That novel you are writing, that art-form you are creating, that movement you are pioneering, that company you are founding or that book you are launching has a very low likelihood of succeeding.
A voice inside us that knows this fills us with fear and hesitation. So do our friends, relatives and other well-wishers. Yet, with each of those pursuits, we must act as if our chances of succeeding are high. This necessary delusion gives us the hope to persevere despite the low likelihood of success.
It is important to take our chances, for in the long-term we regret not having tried more than we regret failure.